1. 个人简历
李林，汉族，中共党员，国家级青年人才，教授，博导。2000-2009年在安徽大学化学化工学院完成本硕博连读，2009-2014年于新加坡国立大学化学系Yao Shao Q.教授课题组从事博士后研究工作；2014年全职回国加盟南京工业大学先进材料研究院（IAM）黄维院士团队；2023年加盟厦门大学柔性电子（未来技术）研究院（IFE）。课题组聚焦“线粒体抗衰老”研究。迄今为止，在Nature Communications、Journal of the American Chemical Society、Angewandte Chemie International Edition、Advanced Materials等期刊上累计发表论文300余篇，申请/授权发明专利62/30项，参与编撰专著《分子影像与精准诊断》。
2. 研究方向
（1）线粒体质量评价与控制
（2）柔性电子健康监测器件
3. 奖励荣誉（省部级以上奖励）
2014年当选江苏特聘教授；
2015年入选国家青年千人计划；
2016年获得江苏省杰出青年基金支持；
2022年当选闽江特聘教授；
2023年入选福建省高层次人才计划；
主持国家级项目3项，省部级项目8项，企业等委托项目10项。
4. 学术兼职
“中国青年化学家-元素周期表-Mc元素”代言人；
“人工智能学会智能健康电子专委会”秘书长；
“中国生物医学工程学会生物医学光子学专委会”常委；
“中国环境诱变剂学会活性氧生物学效应专委会”委员；
“新加坡神经医学研究院（NNI）”客座研究员；
5. 近期代表作
1. Ding Y,† Li J,† Zhang J, Li P, Bai H, Fang B, Fang H, Huang K, Wang G, Nowell C, Voelcker N, Peng B*, Li L* & Huang W*, Mitochondrial segmentation and function prediction in live-cell images with deep learning, Nature Communications, 2025.
2. Fang B,† Bai H,† Zhang J,† Wang L, Si M, Ge Y, Ding Y, Li P, Zhang D, Fang H, Huang Z, Su X, Ding A, Peng B, Chen X*, Li L* & Huang W*, Fluorogen-activating human serum albumin for mitochondrial nanoscale imaging, Advanced Materials 2025.
3. Li P,† Zhang J,† Shao T,† Jiang J, Tang X, Yang J, Li J, Fang B, Huang Z, Fang H, Wang H, Hu W, Peng B*, Bai H* & Li L* NIR-II Photosensitizer Defunctionalizing Mitochondria to Overcome Tumor Self-defense by Promoting Heat-shock Protein 40, ACS Nano 2025.
4. Fang Z,† Zhang J,† Shi Z,† Wang L, Liu Y, Wang J, Jiang J, Yang D, Bai H, Peng B, Wang H, Huang X, Li J*, Li L* & Huang W*, A gas/phototheranostic nanocomposite integrates NIR-II-peak absorbing Aza-BODIPY with thermal-sensitive nitric oxide donor for atraumatic osteosarcoma therapy, Advanced Materials 2023.
5. Li M,† Lu Z,† Zhang J,† Chen L, Tang X, Jiang Q, Hu Q*, Li L*, Liu J* & Huang W*, Near-Infrared-II fluorophore with inverted dependence of fluorescence quantum yield as potent phototheranostics for fluorescence image-guided phototherapy of tumors, Advanced Materials 2023.
6. Zhang C,† Fang H,† Du W,† Zhang D, Qu Y, Tang F, Ding A, Huang K, Peng B*, Li L* & Huang W*, Ultrafast detection of monoamine oxidase a in live cells and clinical glioma tissues using an affinity binding-based two-photon fluorogenic probe, Angewandte Chemie International Edition 2023. (Hot paper)
7. Liu H,† Zhao J,† Xue Y*, Zhang J, Bai H, Pan S, Peng B*, Li L* & Voelcker N, X-ray-induced drug release for cancer therapy, Angewandte Chemie International Edition 2023.
8. Zhai R,† Fang B,† Lai Y, Peng B, Bai H, Liu X*, Li L* & Huang W*, Small-molecule fluorogenic probes for mitochondria nanoscale imaging, Chemical Society Reviews 2023. (Front Cover)
9. Pan S,† Ding A,† Li Y, Sun Y, Zhan Y, Ye Z, Song N, Peng B, Li L*, Huang W* & Shao H*, Small-molecule probes from bench to bedside: advancing molecular analysis of drug-target interactions toward precision medicine, Chemical Society Review 2023.
10. Fang B,† Shen Y,† Peng B,† Bai H, Wang L, Zhang J, Hu WB, Fu L, Zhang W*, Li L* & Huang W*, Small-molecule quenchers for förster resonance energy transfer: structure, mechanism, and applications, Angewandte Chemie International Edition 2022.
11. Ji W,† Tang X,† Lu Y, Wu Q,* Yang N, Liu J, Yu H, Li L* & Huang W*, Optical/electrical methods for detecting mitochondrial energy metabolism, Chemical Society Reviews 2022. (Front Cover)
12. Ding Y, Li Z, Xu C, Qin W, Wu Q, Wang X, Cheng X,* Li L* & Huang W*, Recent progress of fluorogenic probes/inhibitors of β-lactamase and their applications in drug-resistant bacteria, Angewandte Chemie International Edition 2021.
13. Liew S,† Qin X,*,† Zhou J, Li L*, Huang W* & Yao S*, Smart design of nanomaterials for mitochondria-targeted nanotherapeutics, Angewandte Chemie International Edition 2021.
14. Xue Y,† Bai H,† Fang B, Peng B,* Li L*, Huang W* & Voelcker N*, Stimulus-cleavable linker chemistry in the field of controlled drug delivery, Chemical Society Reviews 2021. (Front Cover)
15. Guo X,† Yang N,† Zhang H, Ji W, Dong X, Shen H, Li L*, Yao S* & Huang W*, Mito-bomb: targeting the mitochondria for cancer therapies, Advanced Materials 2021.
16. Fang H, Zhang H, Li L*, Ni Y, Shi R, Li Z, Ma B, Zhang C, Wu Q, Yu C, Yang N, Yao S* & Huang W*, Rational design of a two-photon fluorogenic probe for visualizing monoamine oxidase activity in human glioma tissues, Angewandte Chemie International Edition 2020. (Hot paper)
17. Shi Z, Han X, Hu W*, Bai H, Peng B, Ji L, Fan Q, Li L* & Huang W*, Bioapplications of small molecular aza-BODIPY: from rational structure design to in vivo investigations, Chemical Society Reviews 2020. (Front Cover)
18. Wang L,† Du W,† Hu Z, Uvdal K, Li L* & Huang W*, Hybrid rhodamine fluorophores in the visible-NIR region for biological imaging, Angewandte Chemie International Edition 2019.
19. Yuan P, Mao X, Wu X, Liew S, Li L* & Yao S*, Mitochondria-targeted intracellular delivery of native proteins by using biodegradable silica nanoparticles, Angewandte Chemie International Edition 2019.
20. Qian L, Fu J, Yuan P, Du S, Huang W, Li L* & Yao S*, Intracellular delivery of native proteins facilitated by cell-penetrating poly(disulfide)s, Angewandte Chemie International Edition 2018. (Front Cover)
