
1. 个人简历
郝凯,汉族,群众,助理教授。2016年和2021年在吉林大学和中国科学技术大学(中国科学院长春应用化学研究所)分别获学士和博士学位;2025年起在厦门大学担任助理教授。先后在Advanced Materials、ACS Nano等国际知名期刊上发表研究论文近17篇,授权国内专利2项。
2. 联系方式
kaihao@xmu.edu.cn
3.研究方向
课题组的研究方向集中在
(1)生物医用高分子材料的设计、制备和产业化
(2)高分子药物载体纳米化研究
(3)核酸药物的特定器官和细胞器靶向递送
(4)抗肿瘤免疫治疗和传染病防治
4.近期代表作(代表性成果,最多20篇):
1. Meng M, Wu JY, Feng YJ, Lin L, Chen J, Pang X, Li YH, Hao K*, Tian HY*, and Chen XS, A Comprehensive Strategy Based on High Clinical Translational Nanosystem for Programmable Immunotherapy of Triple Negative Breast Cancer. Advanced Materials, 2024, 36:2134309.
2. Meng M, Wu JY, Guo XY, Li T, Yue PH, Tu ZY, Wu RY, Xing YM, Li F, Cao QN, Li KY, Shang LD, Chen J, Pang X, Li YH, Hao K*, Tian HY*, Chen XS, An Injectable Photothermal-Fusing Hydrogel: Achieving Temperature-Controllable Mild Photothermal Therapy to Reverse Chemotherapy-Induced Immune Tolerance. Nano Letters, 2024, 24:13044.
3. Li Z, Feng YJ, Zhang SJ, Li T, Li HX, Wang DW, Hao K*, He CL, Tian HY*, Chen XS, A Multifunctional Nanoparticle Mitigating Cytokine Storm by Scavenging Multiple Inflammatory Mediators of Sepsis. ACS Nano, 2023, 17:8551.
4. Zhang SJ, Feng YJ, Meng M, Li Z, Li HX, Lin L, Xu CN, Chen J, Hao K*, Tang ZH, Tian HY*, Chen XS, A generally minimalist strategy of constructing biomineralized high-efficiency personalized nanovaccine combined with immune checkpoint blockade for cancer immunotherapy. Biomaterials, 2022, 289:121794.
5. Li T, Wang DW, Meng M, Guo XY, Lin L, Yang ZY, Li Z, Xiang LW, Liu C, Chen J, Pang X, Hao K*, Tian HY*, Chen XS, Dual regulation of the orderly aggregation of covalent organic frameworks at the molecular level and nanoscale to achieve efficient phototherapy and gene therapy. Chemical Engineering Journal, 2024, 492:152163.
6. Hao K, Guo ZP, Lin L, Sun PJ, Li YH*, Tian HY*, Xuesi Chen, Covalent organic framework nanoparticles for anti-tumor gene therapy. Science China Chemistry, 2021, 64:1235.
7. Yuan YN, Luo ZH, Chen J, He CL, Hao K*, Tian HY*, Constructing thermoresponsive PNIPAM-based microcarriers for cell culture and enzyme-free cell harvesting. Chinese Chemical Letters, 2024, 35:109549.