1. 个人简历
潘思骏，汉族，国家级高层次青年人才，福建省引进高层次创新人才，教授，博士生导师。2012年在新加坡南洋理工大学化学与生物化学系获学士学位；2017年在新加坡国立大学化学系获博士学位，随后在新加坡国立大学健康创新与技术研究院从事博士后研究；2023年加入厦门大学柔性电子（未来技术）研究院，历任副教授、教授。先后在Nature Nanotechnology、Nature Biomedical Engineering、Angewandte Chemie International Edition、Chemical Society Reviews等国际知名期刊上发表研究论文20余篇，授权国际专利2项。
2. 联系方式
邮箱：ifesjpan@xmu.edu.cn
3. 研究方向
潘思骏教授课题组的研究领域为健康电子、分子探针、生物传感、外泌体/细胞外囊泡和体外诊断，研究方向集中在外泌体药靶信息检测与肺癌精准诊疗：
（1）针对药物-靶点相互作用构建功能化、特异性分子探针，实现高时空分辨的原位成像与定量分析，研究药效机制和预测方法；
（2）结合分子探针和生物光学传感发展超灵敏外泌体药靶信息检测技术，识别反映癌细胞药效机制的外泌体生物标志物及其集成指标；
（3）发展快速多参数的肺癌外泌体血检平台，建立基于外泌体药靶信息的肺癌治疗响应监测和早期评价模型，推进外泌体即时检测技术转化和临床应用。
4. 近期代表作
1. Pan S, Zhang Y, Natalia A, Lim CZJ, Ho NRY, Chowbay B, Loh TP, Tam JKC, Shao H*, Extracellular vesicle drugoccupancy enables real-time monitoring of targeted cancer therapy, Nature Nanotechnology 2021.
2. Zhao H†, Pan S†, Natalia A, Wu X, Ong CJ, Teo MCC, So JBY, Shao H*, A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples, Nature Biomedical Engineering 2023.
3. Fang H, Li P, Shen C, Tang FY, Ding A, Bai H, Peng B, Yang X, Li Z, Huang K, Pan S*, Li L*, Huang W*, A fluorogenic-inhibitor-based probe for profiling and imaging of monoamine oxidase A in live human glioma cells and clinical tissues, Science China Chemistry 2023.
4. Pan S†, Ding A†, Li Y, Sun Y, Zhan Y, Ye Z, Song N, Peng B, Li L,* Huang W,* Shao H.* Small-molecule probes from bench to bedside: advancing molecular analysis of drug–target interactions toward precision medicine. Chemical Society Reviews 2023.
5. Ye Y, Sun J, Tang F, Xie R, Wang H, Ding A*, Pan S*, Li L*, Mitochondria-targeting BODIPY probes for imaging of reactive oxygen species, Advanced Sensor Research 2023.
6. Qian L*, Pan S, Lee JS, Ge J, Li L*, Yao SQ*, Live-cell imaging and profiling of c-Jun N-terminal kinases using covalent inhibitor-derived probes, Chemical Communications 2019.
7. Pan S, Jang SY, Liew SS, Fu J, Wang D, Lee JS*, Yao SQ*, A vinyl sulfone-based fluorogenic probe capable of selective labeling of PHGDH in live mammalian cells, Angewandte Chemie International Edition 2018.
8. Pan S, Jang SY, Wang D, Liew SS, Li Z, Lee JS*, Yao SQ*, A suite of "minimalist" photo-crosslinkers for live-cell imaging and chemical proteomics: case study with BRD4 Inhibitors, Angewandte Chemie International Edition 2017.
9. Pan S, Zhang H, Wang C, Yao SC, Yao SQ*, Target identification of natural products and bioactive compounds using affinity-based probes, Nature Product Reports 2016.
10. Na Z, Pan S, Uttamchandani M, Yao SQ*, Discovery of cell‐permeable inhibitors that target the BRCT domain of BRCA1 protein by using a small‐molecule microarray, Angewandte Chemie International Edition 2014.
